Sitagliptin fosfat Asosiy ma'lumotlar
| Mahsulot nomi: | Sitagliptin fosfat |
| Sinonimlar: | (3R)-3-aMino-1-[3-(trifloroMetil)-5H,6H,7H,8H-[1,2,4]triazolo[4,{{13} }}a]pirazin-7-il]-4-(2,4,5-triflorofenil)butan-1-bir;Sitagliptin fosfat/Sitagliptin fosfat monogidrat/Sitagliptin;Sitagliptin fosfat {{ 20}}Okso-4-(3-(triflorometil)-5,6-dihidro(1,2,4)triazolo[4,3-a]pirazin{ {30}}(8H)-il)-1-(2,4,5-triflorofenil)butan-2-aminfosfat;3-amino-1-({{ 40}}(triflorometil)-5,6-dihidro-[1,2,4]triazolo[4,3-a]-pirazin-7(8H)-il) -4-(2,4,5-t;sitagpliptin;4-Okso-4-(3-(triflorometil)-5,6- dihidro(1,2,4)triazolo[4,3-a]pirazin-7(8H)-il)-1-(2,4,5-triflorofenil)butan{ {74}}aminfosfat;Sitagliptin fosfat;7-[(3R)-3-Amin-1-okso-4-(2,4,5-triflorofenil)butil] -5,6,7,8-tetrahidro-3-(triflorometil)-1,2,4-triazolo[4,3-]pirazin-fosfat |
| CAS: | 654671-78-0 |
| MF: | C16H18F6N5O5P |
| MVt: | 505.31 |
| EINECS: | 1806241-263-5 |
Sitagliptin fosfatning kimyoviy xossalari
| Erish nuqtasi | 202-204 daraja |
| saqlash harorati. | -20 daraja muzlatgich |
| eruvchanligi | Metanol (ozgina, isitiladi), suv (tejamkor, soniklangan) |
| shakl | Qattiq |
| rang | Oqdan xira oqgacha |
Sitagliptin fosfatdan foydalanish va sintez
| Tavsif | Sitagliptin 2-toifa diabetni vazn ortishisiz davolash uchun Merck kompaniyasining birinchi yangi dipeptidil peptidaza IV inhibitori bo'lib, gipoglikemiya tez-tezligi platseboga o'xshash edi. Sitagliptin tananing inkretin tizimini kuchaytirish orqali harakat qiladi, bu oshqozon osti bezi hujayralari va hujayralariga ta'sir qilish orqali glyukoza miqdorini tartibga solishga yordam beradi. |
| Kimyoviy xossalari | Oq qattiq |
| Foydalanadi | Trizolopirazin dipeptidil peptidaz IV inhibitori. Yaqinda u II turdagi diabetni davolash uchun tasdiqlangan. |
Issiq teglar: sitagliptin fosfat cas no.654671-78-0, Xitoy, ishlab chiqaruvchilar, etkazib beruvchilar, zavod, buyurtma, ulgurji
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